Reconstruction of a Comprehensive Interactome and Experimental Data Analysis of FRA10AC1 May Provide Insights into Its Biological Role in Health and Disease

Reconstruction of a Comprehensive Interactome and Experimental Data Analysis of FRA10AC1 May Provide Insights into Its Biological Role in Health and Disease

<i>FRA10AC1</i>, the causative gene for the manifestation of the <i>FRA10A</i> fragile site, encodes a well-conserved nuclear protein characterized as a non-core spliceosomal component. Pre-mRNA splicing perturbations have been linked with neurodevelopmental diseases. <i&g...

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Bibliographic Details
Main Authors: Theologia Sarafidou, Eleni Galliopoulou, Despina Apostolopoulou, Georgios A. Fragkiadakis, Nicholas K. Moschonas
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Genes
Subjects:
spliceosome
expression profile
protein interactome
disease-protein network
RNA in situ hybridization
protein interactions methods
Online Access:https://www.mdpi.com/2073-4425/14/3/568

Internet

https://www.mdpi.com/2073-4425/14/3/568

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