Repertoire-scale determination of class II MHC peptide binding via yeast display improves antigen prediction

Identifying peptides that can bind major histocompatibility complex II (MHC-II) is important for our understanding of T cell immunity and specificity. Here the authors present a yeast-display library screening approach that identifies more potential binders than various reported algorithms to help e...

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Bibliographic Details
Main Authors: C. Garrett Rappazzo, Brooke D. Huisman, Michael E. Birnbaum
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18204-2