Repertoire-scale determination of class II MHC peptide binding via yeast display improves antigen prediction
Identifying peptides that can bind major histocompatibility complex II (MHC-II) is important for our understanding of T cell immunity and specificity. Here the authors present a yeast-display library screening approach that identifies more potential binders than various reported algorithms to help e...
Main Authors: | C. Garrett Rappazzo, Brooke D. Huisman, Michael E. Birnbaum |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-18204-2 |
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