Postsynaptic protein synthesis is required for presynaptic enhancement in persistent forms of long-term potentiation.

Long-term potentiation (LTP) in the hippocampus is a fundamental process underlying learning and memory in the brain. At CA3-CA1 synapses, three discrete forms of LTP (LTP1, 2 and 3) have been differentiated on the basis of their persistence, maintenance mechanisms, Ca2+ signaling pathways, express...

Full description

Bibliographic Details
Main Authors: Victoria Philippa Anne Johnstone, Clarke Robert Raymond
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2013.00001/full