Adriamycin-induced podocyte injury via the Sema3A/TRPC5/Rac1 pathway

Podocytopathies encompass kidney diseases where direct or indirect podocyte injury leads to proteinuria or nephrotic syndrome. Although Semaphorin3A (Sema3A) is expressed in podocytes and tubular cells in adult mammalian kidneys and has a common effect on the progression of podocyte injury, its mech...

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Bibliographic Details
Main Authors: Yan Liu, Ri-Li Ge, Zhen-Zhen Shan, Yan-Jun Wang, Yan-Yan Yang, Xue Sun, Peng-Li Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1381479/full