Network pharmacology and subsequent experimental validation reveal the synergistic myocardial protection mechanism of Salvia miltiorrhiza Bge. and Carthamus tinctorius L.

Network pharmacology and subsequent experimental validation reveal the synergistic myocardial protection mechanism of Salvia miltiorrhiza Bge. and Carthamus tinctorius L.

Objective: To reveal the molecular mechanism underlying the compatibility of Salvia miltiorrhiza Bge (S. miltiorrhiza, Dan Shen) and C. tinctorius L. (C. tinctorius, Hong Hua) as an herb pair through network pharmacology and subsequent experimental validation. Methods: Network pharmacology was appli...

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Bibliographic Details
Main Authors: Linying Zhong, Ling Dong, Jing Sun, Jie Yang, Zhiying Yu, Ping He, Bo Zhu, Yuxin Zhu, Siyuan Li, Wenjuan Xu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
S. miltiorrhiza-C. tinctorius herb pair
Compatibility mechanism
Network pharmacology
Multiple target effect
Myocardial protection
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754823000741

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http://www.sciencedirect.com/science/article/pii/S2095754823000741

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