Efficient Catalytic Synthesis of Condensed Isoxazole Derivatives via Intramolecular Oxidative Cycloaddition of Aldoximes

Efficient Catalytic Synthesis of Condensed Isoxazole Derivatives via Intramolecular Oxidative Cycloaddition of Aldoximes

The intramolecular oxidative cycloaddition reaction of alkyne- or alkene-tethered aldoximes was catalyzed efficiently by hypervalent iodine(III) species to afford the corresponding polycyclic isoxazole derivatives in up to a 94% yield. The structure of the prepared products was confirmed by various...

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Bibliographic Details
Main Authors: Irina A. Mironova, Valentine G. Nenajdenko, Pavel S. Postnikov, Akio Saito, Mekhman S. Yusubov, Akira Yoshimura
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
hypervalent iodine
hydroxy(aryl)iodonium
catalysis
aldoximes
intramolecular cycloaddition
nitrogen heterocycles
Online Access:https://www.mdpi.com/1420-3049/27/12/3860

Internet

https://www.mdpi.com/1420-3049/27/12/3860

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