Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening.

Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening.

BACKGROUND: The subcellular localization of membrane and secreted proteins is finely and dynamically regulated through intracellular vesicular trafficking for permitting various biological processes. Drosophila Amyloid precursor protein like (APPL) and Hikaru genki (HIG) are examples of proteins tha...

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Bibliographic Details
Main Authors: Masaki Sone, Atsuko Uchida, Ayumi Komatsu, Emiko Suzuki, Ikue Ibuki, Megumi Asada, Hiroki Shiwaku, Takuya Tamura, Mikio Hoshino, Hitoshi Okazawa, Yo-ichi Nabeshima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2635962?pdf=render

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http://europepmc.org/articles/PMC2635962?pdf=render

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