Investigation of Rare Non-Coding Variants in Familial Multiple Myeloma

Investigation of Rare Non-Coding Variants in Familial Multiple Myeloma

Multiple myeloma (MM) is a plasma cell malignancy whereby a single clone of plasma cells over-propagates in the bone marrow, resulting in the increased production of monoclonal immunoglobulin. While the complex genetic architecture of MM is well characterized, much less is known about germline varia...

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Bibliographic Details
Main Authors: Yasmeen Niazi, Nagarajan Paramasivam, Joanna Blocka, Abhishek Kumar, Stefanie Huhn, Matthias Schlesner, Niels Weinhold, Rolf Sijmons, Mirjam De Jong, Brian Durie, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
non-coding genome
familial multiple myeloma
MAPK pathway
whole-genome sequencing
Online Access:https://www.mdpi.com/2073-4409/12/1/96

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https://www.mdpi.com/2073-4409/12/1/96

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