Anti-Diabetic Effect of Organo-Chalcogen (Sulfur and Selenium) Zinc Complexes with Hydroxy-Pyrone Derivatives on Leptin-Deficient Type 2 Diabetes Model ob/ob Mice

Anti-Diabetic Effect of Organo-Chalcogen (Sulfur and Selenium) Zinc Complexes with Hydroxy-Pyrone Derivatives on Leptin-Deficient Type 2 Diabetes Model ob/ob Mice

Since the discovery of the anti-diabetic effects of zinc (Zn) complex, we synthesized several Zn complexes and evaluated their effects using the KKAy type 2 diabetes mouse model. Recently, we demonstrated that organo-chalcogen (sulfur and selenium) Zn complexes elicit strong anti-diabetic effects. I...

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Bibliographic Details
Main Authors: Takayuki Nishiguchi, Yutaka Yoshikawa, Hiroyuki Yasui
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes mellitus
organo-chalcogen zinc complexes
ob/ob mice
anti-diabetic effect
inductively coupled plasma mass spectrometry
morphological analysis
Online Access:https://www.mdpi.com/1422-0067/18/12/2647

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https://www.mdpi.com/1422-0067/18/12/2647

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