Ginsenoside Rg1 attenuates chronic inflammation-induced renal fibrosis in mice by inhibiting AIM2 inflammasome in an Nrf2-dependent manner

Ginsenoside Rg1 attenuates chronic inflammation-induced renal fibrosis in mice by inhibiting AIM2 inflammasome in an Nrf2-dependent manner

Chronic kidney disease (CKD) is a growing global public health issue. Ginsenoside Rg1 (Rg1) has favorable nephroprotective effects, but its role and mechanism in CKD need further investigation. Therefore, we observed the effect of Rg1 on the mouse kidneys after 21 days of low-dose lipopolysaccharide...

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Bibliographic Details
Main Authors: Pengmin Ji, Qifeng Shi, Liangliang Kong, Yan Liu, Yong Su, Ran Sun, Huimin Zhou, Hanyang Xu, Weiping Li, Weizu Li
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Functional Foods
Subjects:
Ginsenoside Rg1
Nrf2/HO-1 pathway
AIM2 inflammasomes
Chronic inflammation
Chronic kidney disease
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624002068

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http://www.sciencedirect.com/science/article/pii/S1756464624002068

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