Chromomycins A2 and A3 from Marine Actinomycetes with TRAIL Resistance-Overcoming and Wnt Signal Inhibitory Activities

A biological screening study of an actinomycetes strain assembly was conducted using a cell-based cytotoxicity assay. The CKK1019 strain was isolated from a sea sand sample. Cytotoxicity-guided fractionation of the CKK1019 strain culture broth, which exhibited cytotoxicity, led to the isolation of c...

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Bibliographic Details
Main Authors: Kazufumi Toume, Kentaro Tsukahara, Hanako Ito, Midori A. Arai, Masami Ishibashi
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/6/3466