Effects of nitric oxide synthase inhibitor ω-Nitro-L-Arginine Methyl Ester, on silica-induced inflammatory reaction and apoptosis

<p>Abstract</p> <p>Background</p> <p>Although nitric oxide is overproduced by macrophages and neutrophils after exposure to silica, its role in silica-induced inflammatory reaction and apoptosis needs further clarification. In this study, rats were intratracheally insti...

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Bibliographic Details
Main Authors: Leigh James, Wang He
Format: Article
Language:English
Published: BMC 2006-11-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/3/1/14