Pro-Apoptotic and Anti-Invasive Properties Underscore the Tumor-Suppressing Impact of Myoglobin on a Subset of Human Breast Cancer Cells

Pro-Apoptotic and Anti-Invasive Properties Underscore the Tumor-Suppressing Impact of Myoglobin on a Subset of Human Breast Cancer Cells

The expression of myoglobin (MB), well known as the oxygen storage and transport protein of myocytes, is a novel hallmark of the luminal subtype in breast cancer patients and correlates with better prognosis. The mechanisms by which MB impacts mammary tumorigenesis are hitherto unclear. We aimed to...

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Bibliographic Details
Main Authors: Mostafa A. Aboouf, Julia Armbruster, Markus Thiersch, Franco Guscetti, Glen Kristiansen, Peter Schraml, Anne Bicker, Ruben Petry, Thomas Hankeln, Max Gassmann, Thomas A. Gorr
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
tumorigenesis
migration
apoptosis
ROS
estrogen receptor
hypoxia
Online Access:https://www.mdpi.com/1422-0067/23/19/11483

Internet

https://www.mdpi.com/1422-0067/23/19/11483

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