Large-scale functional RNAi screen in <it>C. elegans </it>identifies genes that regulate the dysfunction of mutant polyglutamine neurons

<p>Abstract</p> <p>Background</p> <p>A central goal in Huntington's disease (HD) research is to identify and prioritize candidate targets for neuroprotective intervention, which requires genome-scale information on the modifiers of early-stage neuron injury in HD.&...

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Bibliographic Details
Main Authors: Lejeune François-Xavier, Mesrob Lilia, Parmentier Frédéric, Bicep Cedric, Vazquez-Manrique Rafael P, Parker J Alex, Vert Jean-Philippe, Tourette Cendrine, Neri Christian
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/13/91