Genes Associated with Disturbed Cerebral Neurogenesis in the Embryonic Brain of Mouse Models of Down Syndrome

Down syndrome (DS), also known as trisomy 21, is the most frequent genetic cause of intellectual disability. Although the mechanism remains unknown, delayed brain development is assumed to be involved in DS intellectual disability. Analyses with human with DS and mouse models have shown that defects...

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Bibliographic Details
Main Author: Keiichi Ishihara
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/10/1598