Brimonidine Modulates the ROCK1 Signaling Effects on Adipogenic Differentiation in 2D and 3D 3T3-L1 Cells

Brimonidine Modulates the ROCK1 Signaling Effects on Adipogenic Differentiation in 2D and 3D 3T3-L1 Cells

The additive effects of an α2-adrenergic agonist, brimonidine (BRI), on the pan-ROCK inhibitor (ROCK-i), ripasudil (Rip), and the ROCK2-I, KD025, on adipogenic differentiation (DIF+) were examined using two- or three-dimension (2D or 3D) cultures of 3T3-L1 cells. The following analyses were carried...

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Bibliographic Details
Main Authors: Araya Umetsu, Yosuke Ida, Tatsuya Sato, Megumi Watanabe, Yuri Tsugeno, Masato Furuhashi, Fumihito Hikage, Hiroshi Ohguro
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Bioengineering
Subjects:
deepening of the upper eyelid sulcus (DUES)
3T3-L1cells
ROCK
Rho-kinase
ROCK inhibitor
3-dimension (3D) tissue culture
Online Access:https://www.mdpi.com/2306-5354/9/7/327

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https://www.mdpi.com/2306-5354/9/7/327

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