Modelling α-synuclein processing in primary patient cells for pharmacological intervention

Modelling α-synuclein processing in primary patient cells for pharmacological intervention

Aim: Parkinson’s disease (PD) is a complex, chronic neurodegenerative disorder with predominately sporadic etiology. Intricate genetic-environmental interactions lead to the hallmarks of the disease: degeneration of dopaminergic neurons and the deposition of α-synuclein aggregates. The aim of this s...

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Bibliographic Details
Main Authors: Jessica K. Smith, George D. Mellick, Alex M. Sykes
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2023-10-01
Series:Exploration of Medicine
Subjects:
α-synuclein
parkinson’s disease
protein trafficking
cell model
drug screen
Online Access:https://www.explorationpub.com/Journals/em/Article/1001170

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https://www.explorationpub.com/Journals/em/Article/1001170

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