Laboratory studies for paroxysmal nocturnal hemoglobinuria, with emphasis on flow cytometry

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired clonal hematopoietic stem cell disorder caused by somatic mutations in the PIG-A gene, leading to the production of blood cells with absent or decreased expression of glycosylphosphatidylinositol-anchored proteins, including CD55 and CD59....

Full description

Bibliographic Details
Main Author: Margarida Lima
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Practical Laboratory Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551719300927