Laboratory studies for paroxysmal nocturnal hemoglobinuria, with emphasis on flow cytometry
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired clonal hematopoietic stem cell disorder caused by somatic mutations in the PIG-A gene, leading to the production of blood cells with absent or decreased expression of glycosylphosphatidylinositol-anchored proteins, including CD55 and CD59....
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Format: | Article |
Language: | English |
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Elsevier
2020-05-01
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Series: | Practical Laboratory Medicine |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2352551719300927 |