Development and in vitro evaluation of Letrozole loaded biodegradable nanoparticles for breast cancer therapy

The objectives of our study were to prepare and evaluate a biodegradable nanoparticulate system of Letrozole (LTZ) intended for breast cancer therapy. LTZ loaded poly(lactide-co-glycolide) nanoparticles (LTZ-PLGA-NPs) were prepared by emulsion-solvent evaporation method using methylene chloride and...

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Bibliographic Details
Main Authors: Sanjoy Kumar Dey, Bivash Mandal, Manas Bhowmik, Lakshmi Kanta Ghosh
Format: Article
Language:English
Published: Universidade de São Paulo 2009-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300025