Characterization of Stability and Small-scale Structural Differences of Intact Glycoprotein Complexes Using Native Mass Spectrometry Travelling-Wave Ion Mobility Spectrometry

Characterization of Stability and Small-scale Structural Differences of Intact Glycoprotein Complexes Using Native Mass Spectrometry Travelling-Wave Ion Mobility Spectrometry

Glycosylation is one of the most common types of post-translational modifications (PTMs) of proteins, which affects protein properties including conformation, stability and solubility, and plays essential roles in functions including molecular recognition, signaling and immune defense. Characterizin...

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Bibliographic Details
Main Authors: XU Xiang1,2, CHAIHU Ling-xiao1, WANG Guan-bo2,3
Format: Article
Language:English
Published: Editorial Board of Journal of Chinese Mass Spectrometry Society 2022-09-01
Series:Zhipu Xuebao
Subjects:
ion mobility (im)
native mass spectrometry (nms)
glycoprotein
protein complex
charge manipulation
Online Access:http://www.jcmss.com.cn/CN/article/openArticlePDF.jsp?attachType=PDF&id=3102

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