Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases

Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases

Neurological and neurodegenerative diseases are debilitating conditions, and frequently lack an effective treatment. Monoacylglycerol lipase (MAGL) is a key enzyme involved in the metabolism of 2-AG (2-arachidonoylglycerol), a neuroprotective endocannabinoid intimately linked to the generation of pr...

Full description

Bibliographic Details
Main Authors: Anca Zanfirescu, Anca Ungurianu, Dragos Paul Mihai, Denise Radulescu, George Mihai Nitulescu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
monoacylglycerol-lipase inhibitors
2-arachidonoylglycerol
neuroinflammation
neurodegenerative disorders
carbamates
irreversible inhibitors
Online Access:https://www.mdpi.com/1420-3049/26/18/5668

Internet

https://www.mdpi.com/1420-3049/26/18/5668

Similar Items