Development of Liposomal Formulations of Zinc Diethyldithiocarbamate for Colorectal Cancer Treatment

(DDC)2Zn, disulfiram (DS) metabolite, has shown promising anticancer effects in vitro but further investigations in vivo are limited by its poor water solubility. In this study, liposomes are assessed as a delivery system for (DDC)2Zn. Liposomes were prepared by the thin-film hydration method, follo...

Full description

Bibliographic Details
Main Authors: Niusha Ansari-Fard, Ayse Kaya, Dan Alves, Basel Arafat, Barbara Pierscionek, Mohammad Najlah
Format: Article
Language:English
Published: University of Huddersfield Press 2022-11-01
Series:British Journal of Pharmacy
Subjects:
Online Access:https://www.bjpharm.org.uk/article/id/1148/