Rabies virus P protein binds to TBK1 and interferes with the formation of innate immunity-related liquid condensates

Rabies virus P protein binds to TBK1 and interferes with the formation of innate immunity-related liquid condensates

Summary: Viruses must overcome the interferon-mediated antiviral response to replicate and propagate into their host. Rabies virus (RABV) phosphoprotein P is known to inhibit interferon induction. Here, using a global mass spectrometry approach, we show that RABV P binds to TBK1, a kinase located at...

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Bibliographic Details
Main Authors: Nathalie Scrima, Romain Le Bars, Quentin Nevers, Damien Glon, Guillaume Chevreux, Ahmet Civas, Danielle Blondel, Cécile Lagaudrière-Gesbert, Yves Gaudin
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722018502

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http://www.sciencedirect.com/science/article/pii/S2211124722018502

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