Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 Protocol

Hyperleukocytosis (HL) in pediatric acute myeloid leukemia (AML) is associated with severe complications and inferior outcome. We report results on HL patients included in the NOPHO-DBH AML 2012 study. We recommended immediate start of full dose chemotherapy (etoposide [ETO] monotherapy for 5 days...

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Main Authors: Bernward Zeller, Nira Arad-Cohen, Daniel Cheuk, Barbara De Moerloose, Jose M. Fernandez Navarro, Henrik Hasle, Kirsi Jahnukainen, Kristian Lovvik Juul-Dam, Gertjan Kaspers, Zanna Kovalova, Olafur G. Jonsson, Birgitte Lausen, Monica Munthe-Kaas, Ulrika Noren Nystrom, Josefine Palle, Ramune Pasauliene, Cornelis J. Pronk, Kadri Saks, Anne Tierens, Jonas Abrahamsson
Format: Article
Language:English
Published: Ferrata Storti Foundation 2024-05-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11587