Release kinetics of metronidazole from 3D printed silicone scaffolds for sustained application to the female reproductive tract

Release kinetics of metronidazole from 3D printed silicone scaffolds for sustained application to the female reproductive tract

Sustained vaginal administration of antibiotics or probiotics has been proposed to improve treatment efficacy for bacterial vaginosis. 3D printing has shown promise for development of systems for local agent delivery. In contrast to oral ingestion, agent release kinetics can be fine-tuned by the 3D...

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Bibliographic Details
Main Authors: Sydney E. Herold, Anthony J. Kyser, Margaret G. Orr, Mohamed Y. Mahmoud, Warren G. Lewis, Amanda L. Lewis, Jill M. Steinbach-Rankins, Hermann B. Frieboes
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biomedical Engineering Advances
Subjects:
Metronidazole
3D printed scaffolds
Silicone scaffolds
Drug release kinetics
Bacterial vaginosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2667099223000087

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http://www.sciencedirect.com/science/article/pii/S2667099223000087

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