Lack of immunogenicity of xenogeneic DNA from porcine biomaterials

Background: Clinically useful biomaterials are derived from xenogeneic extracellular matrices, but extensive processes often used to remove all residual DNA are detrimental to their proper biological function. We hypothesized that deliberate and repeated injection of DNA extracted from clinically im...

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Bibliographic Details
Main Authors: Rae D. Record Ritchie, PhD, Sharon L. Salmon, BSc, Michael C. Hiles, PhD, Dennis W. Metzger, PhD
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Surgery Open Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2589845022000495