The activity of CCL18 is principally mediated through interaction with glycosaminoglycans

The CC chemokine ligand 18 (CCL18) was first identified as a chemoattractant for naïve T cells. It has been reported to recruit T and B lymphocytes, and we show here, Natural killer (NK) cells, but with low efficacy. Investigation of its ability to elicit G-protein coupled signaling showed...

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Bibliographic Details
Main Authors: Sonja C. Krohn, Alexandre eGarin, Cem eGabay, Amanda E.I. Proudfoot
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00193/full