Impairment of Ceramide-Mediated Endothelial Instant Membrane Resealing During Diabetes Mellitus

Impairment of Ceramide-Mediated Endothelial Instant Membrane Resealing During Diabetes Mellitus

Recent studies have indicated that instant cell membrane resealing (ICMR) controls the activation of NOD-like receptor pyrin domain containing 3 (Nlrp3) inflammasomes in endothelial cells, thereby initiating and promoting vascular inflammation. It remains unknown whether this impaired ICMR occurs un...

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Bibliographic Details
Main Authors: Yang Chen, Guangbi Li, Owais M. Bhat, Xiang Li, Yang Zhang, Pin-Lan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Physiology
Subjects:
membrane repair
sphingolipid
endothelial dysfunction
annexin
hyperglycemia
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.910339/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.910339/full

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