Topical Pirfenidone-Loaded Liposomes Ophthalmic Formulation Reduces Haze Development after Corneal Alkali Burn in Mice

Topical Pirfenidone-Loaded Liposomes Ophthalmic Formulation Reduces Haze Development after Corneal Alkali Burn in Mice

Corneal chemical burns (CCBs) frequently result in corneal fibrosis or haze, an opacity of the cornea that obstructs vision and induces corneal blindness. Diverse strategies have been employed to prevent or reduce CCB-related corneal haze. In this study, we evaluated the physicochemical characterist...

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Bibliographic Details
Main Authors: Carlos Daniel Diaz-Palomera, Isaac Alejandro Vidal-Paredes, Jose Navarro-Partida, Margarita Cid-Hernandez, Luis Carlos Rosales-Rivera, Ricardo De la Rosa-Bibiano, Hugo Christian Monroy-Ramirez, Arturo Santos, Juan Armendariz-Borunda
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
cornea
haze
pirfenidone
liposomes
nanoparticles
Online Access:https://www.mdpi.com/1999-4923/14/2/316

Internet

https://www.mdpi.com/1999-4923/14/2/316

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