Binding of interferon reduces the force of unfolding for interferon receptor 1.
Differential signaling of the type I interferon receptor (IFNAR) has been correlated with the ability of its subunit, IFNAR1, to differentially recognize a large spectrum of different ligands, which involves intricate conformational re-arrangements of multiple interacting domains. To shed light onto...
Main Authors: | Silvia G Chuartzman, Reinat Nevo, Sharon Waichman, Dalit Shental, Jacob Piehler, Yaakov Levy, Ziv Reich, Ruti Kapon |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5389645?pdf=render |
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