Increased Excitability and Heightened Magnitude of Long-Term Potentiation at Hippocampal CA3–CA1 Synapses in a Mouse Model of Neonatal Hyperoxia Exposure

Preterm infants exposed to supraphysiological oxygen (hyperoxia) during the neonatal period have hippocampal atrophy and cognitive dysfunction later in childhood and as adolescents. Previously, we reported that 14-week-old adult mice exposed to hyperoxia as newborns had spatial memory deficits and h...

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Bibliographic Details
Main Authors: Manimaran Ramani, Kiara Miller, Namasivayam Ambalavanan, Lori L. McMahon
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2020.609903/full