Leishmania tarentolae as Potential Live Vaccine Co-Expressing Distinct Salivary Gland Proteins Against Experimental Cutaneous Leishmaniasis in BALB/c Mice Model

Leishmania tarentolae as Potential Live Vaccine Co-Expressing Distinct Salivary Gland Proteins Against Experimental Cutaneous Leishmaniasis in BALB/c Mice Model

Leishmaniasis is a neglected vector-borne disease caused by Leishmania parasites transmitted through the infected sand flies bite. Current treatments are limited, partly due to their high cost and significant adverse effects, and no human vaccine is yet available. Sand flies saliva has been examined...

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Bibliographic Details
Main Authors: Mahya Sadat Lajevardi, Elham Gholami, Tahereh Taheri, Hamzeh Sarvnaz, Sima Habibzadeh, Negar Seyed, Yousef Mortazavi, Sima Rafati
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
cutaneous leishmaniasis
live vaccine
sand fly
salivary proteins
Leishmania major
Leishmania tropica
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.895234/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.895234/full

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