Toll-like receptor 3: a double-edged sword

Abstract The discovery of Toll-like receptors (TLRs) and their role in dendritic cells earned the Nobel Prize for 2011 because TLRs profoundly enhanced our understanding of the immune system. Specifically, TLR3 is located within the endosomal compartments of dendritic cells and plays a crucial role...

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Bibliographic Details
Main Authors: Marvin L Hsieh, Daisuke Nishizaki, Jacob J Adashek, Shumei Kato, Razelle Kurzrock
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-025-00739-5