From SNPs to genes: disease association at the gene level.

Interpreting Genome-Wide Association Studies (GWAS) at a gene level is an important step towards understanding the molecular processes that lead to disease. In order to incorporate prior biological knowledge such as pathways and protein interactions in the analysis of GWAS data it is necessary to de...

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Bibliographic Details
Main Authors: Benjamin Lehne, Cathryn M Lewis, Thomas Schlitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3128073?pdf=render