Evaluation of Oxidative Stress and Metabolic Profile in a Preclinical Kidney Transplantation Model According to Different Preservation Modalities

Evaluation of Oxidative Stress and Metabolic Profile in a Preclinical Kidney Transplantation Model According to Different Preservation Modalities

This study addresses a joint nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) spectroscopy approach to provide a platform for dynamic assessment of kidney viability and metabolism. On porcine kidney models, ROS production, oxidative damage kinetics, and metabolic changes oc...

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Bibliographic Details
Main Authors: Simona Mrakic-Sposta, Alessandra Vezzoli, Emanuela Cova, Elena Ticcozzelli, Michela Montorsi, Fulvia Greco, Vincenzo Sepe, Ilaria Benzoni, Federica Meloni, Eloisa Arbustini, Massimo Abelli, Maristella Gussoni
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
kidney transplant
hypothermic machine perfusion
organ preservation
ROS
metabolomic
EPR
Online Access:https://www.mdpi.com/1422-0067/24/2/1029

Internet

https://www.mdpi.com/1422-0067/24/2/1029

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