Atorvastatin attenuates ferroptosis-dependent myocardial injury and inflammation following coronary microembolization via the Hif1a/Ptgs2 pathway

Atorvastatin attenuates ferroptosis-dependent myocardial injury and inflammation following coronary microembolization via the Hif1a/Ptgs2 pathway

Objectives: Coronary microembolization (CME) represents a serious periprocedural complication after percutaneous coronary intervention. Ferroptosis has been identified in multiple cardiovascular diseases. In this study, we aimed to investigate the effects of atorvastatin (ATV) on ferroptosis and inf...

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Bibliographic Details
Main Authors: Tao Liu, Jin Shu, Yangchun Liu, Jian Xie, Tao Li, Haoliang Li, Lang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
coronary microembolization
ferroptosis
inflammation
atorvastatin
myocardial injury
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1057583/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1057583/full

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