Nuclear Morphological Remodeling in Human Granulocytes Is Linked to Prenylation Independently from Cytoskeleton

Nuclear Morphological Remodeling in Human Granulocytes Is Linked to Prenylation Independently from Cytoskeleton

Nuclear shape modulates cell behavior and function, while aberrant nuclear morphologies correlate with pathological phenotype severity. Nevertheless, functions of specific nuclear morphological features and underlying molecular mechanisms remain poorly understood. Here, we investigate a nucleus-intr...

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Bibliographic Details
Main Authors: Sebastian Martewicz, Camilla Luni, Xi Zhu, Meihua Cui, Manli Hu, Siqi Qu, Damiano Buratto, Guang Yang, Eleonora Grespan, Nicola Elvassore
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
nuclear morphology
granulocyte lobulation
nuclear segmentation
prenylation
GGTase III
Online Access:https://www.mdpi.com/2073-4409/9/11/2509

Internet

https://www.mdpi.com/2073-4409/9/11/2509

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