HCV IRES-mediated core expression in zebrafish.

The lack of small animal models for hepatitis C virus has impeded the discovery and development of anti-HCV drugs. HCV-IRES plays an important role in HCV gene expression, and is an attractive target for antiviral therapy. In this study, we report a zebrafish model with a biscistron expression const...

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Bibliographic Details
Main Authors: Ye Zhao, Wei Qin, Jing-Pu Zhang, Zhan-Ying Hu, Jun-Wei Tong, Cun-Bao Ding, Zong-Gen Peng, Li-Xun Zhao, Dan-Qing Song, Jian-Dong Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585870?pdf=render