Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice

Astrocytic ApoE underlies maturation of hippocampal neurons and cognitive recovery after traumatic brain injury in mice

Tzong-Shiue Yu et al. assess the impact of astrocytic ApoE on hippocampal neurogenesis and behavior after traumatic brain injury (TBI) in mice. Their results suggest that postnatal ablation of astrocytic APOE reduces dendritic complexity in newborn dentate gyrus neurons and cognitive ability, provid...

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Bibliographic Details
Main Authors: Tzong-Shiue Yu, Yacine Tensaouti, Elizabeth P. Stephanz, Sana Chintamen, Elizabeth E. Rafikian, Mu Yang, Steven G. Kernie
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02841-4

Internet

https://doi.org/10.1038/s42003-021-02841-4

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