Rev-erbα agonist SR9009 protects against cerebral ischemic injury through mechanisms involving Nrf2 pathway

Rev-erbα agonist SR9009 protects against cerebral ischemic injury through mechanisms involving Nrf2 pathway

Backgrounds: The circadian clock protein Rev-erbα is a crucial regulator of circadian rhythms that affects multiple molecular, cellular, and physiology pathways that control susceptibility, injury, and recovery in the neurological disorders. Emerging evidence suggest that Rev-erbα plays a key role i...

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Bibliographic Details
Main Authors: Mingyue Sheng, Xun Chen, Yan Yu, Qi Wu, Junping Kou, Gangling Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
cerebral ischemia
SR9009
REV-erbα
Nrf2
circadian rhythm
circadian gene
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1102567/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1102567/full

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