Lacticaseibacillus rhamnosus GG Counteracts Rotavirus-Induced Ion Secretion and Enterocyte Damage by Inhibiting Oxidative Stress and Apoptosis Through Specific Effects of Living and Postbiotic Preparations

Lacticaseibacillus rhamnosus GG Counteracts Rotavirus-Induced Ion Secretion and Enterocyte Damage by Inhibiting Oxidative Stress and Apoptosis Through Specific Effects of Living and Postbiotic Preparations

BackgroundAdministration of Lacticaseibacillus rhamnosus GG (LGG) to children with gastroenteritis is recommended by universal guidelines. Rotavirus (RV) causes diarrhea through combined cytotoxic and enterotoxic effects. Aim of this study was to evaluate the mechanisms of efficacy of LGG in an in-v...

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Bibliographic Details
Main Authors: Vittoria Buccigrossi, Marco Poeta, Valentina Cioffi, Sara Terranova, Francesco Nunziata, Andrea Lo Vecchio, Alfredo Guarino
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
rotavirus
Lacticaseibacillus rhamnosus GG
gastroenteritis
diarrhea
enterocyte damage
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.854989/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.854989/full

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