Natural Polyphenols May Normalize Hypochlorous Acid-Evoked Hemostatic Abnormalities in Human Blood

Natural Polyphenols May Normalize Hypochlorous Acid-Evoked Hemostatic Abnormalities in Human Blood

During pathogen invasion, activated neutrophils secrete myeloperoxidase (MPO), which generates high local concentrations of hypochlorous acid (HOCl), a strong antimicrobial agent. Prolonged or uncontrolled HOCl production may, however, affect hemostasis, manifesting in inhibition of platelet aggrega...

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Bibliographic Details
Main Authors: Tomasz Misztal, Agata Golaszewska, Natalia Marcińczyk, Maria Tomasiak-Łozowska, Małgorzata Szymanowska, Ewa Chabielska, Tomasz Rusak
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antioxidants
Subjects:
platelets
aggregation
thrombus formation
fibrinolysis
antioxidants
hypochlorous acid
Online Access:https://www.mdpi.com/2076-3921/11/4/779

Internet

https://www.mdpi.com/2076-3921/11/4/779

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