Pax6 organizes the anterior eye segment by guiding two distinct neural crest waves.

Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced the origin of the ocular NC cells to two distinct NC populations that differ in the maintenance of sox10 expression, Wnt signalling, origin, route, mode and destination of mig...

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Bibliographic Details
Main Authors: Masanari Takamiya, Johannes Stegmaier, Andrei Yu Kobitski, Benjamin Schott, Benjamin D Weger, Dimitra Margariti, Angel R Cereceda Delgado, Victor Gourain, Tim Scherr, Lixin Yang, Sebastian Sorge, Jens C Otte, Volker Hartmann, Jos van Wezel, Rainer Stotzka, Thomas Reinhard, Günther Schlunck, Thomas Dickmeis, Sepand Rastegar, Ralf Mikut, Gerd Ulrich Nienhaus, Uwe Strähle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008774