Conformational switches that control the TEC kinase – PLCγ signaling axis

Cell surface receptors such as the T-cell receptor (TCR) and B-cell receptor (BCR) engage with external stimuli to transmit information into the cell and initiate a cascade of signaling events that lead to gene expression that drives the immune response. At the heart of controlling T- and B-cell cel...

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Bibliographic Details
Main Authors: Jacques Lowe, Raji E. Joseph, Amy H. Andreotti
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Structural Biology: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152422000022