Conformational switches that control the TEC kinase – PLCγ signaling axis
Cell surface receptors such as the T-cell receptor (TCR) and B-cell receptor (BCR) engage with external stimuli to transmit information into the cell and initiate a cascade of signaling events that lead to gene expression that drives the immune response. At the heart of controlling T- and B-cell cel...
Main Authors: | Jacques Lowe, Raji E. Joseph, Amy H. Andreotti |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Journal of Structural Biology: X |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590152422000022 |
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