Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway.

Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway.

<h4>Background</h4>The PI3K/AKT pathway plays a pivotal role in breast cancer development and maintenance. PIK3CA, encoding the PI3K catalytic subunit, is the oncogene exhibiting a high frequency of gain-of-function mutations leading to PI3K/AKT pathway activation in breast cancer. PIK3C...

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Bibliografski detalji
Glavni autori: Magdalena Cizkova, Géraldine Cizeron-Clairac, Sophie Vacher, Aurélie Susini, Catherine Andrieu, Rosette Lidereau, Ivan Bièche
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2010-12-01
Serija:PLoS ONE
Online pristup:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21209903/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21209903/pdf/?tool=EBI

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