A Novel Strategy to Study the Invasive Capability of Adherent-Invasive Escherichia coli by Using Human Primary Organoid-Derived Epithelial Monolayers

A Novel Strategy to Study the Invasive Capability of Adherent-Invasive Escherichia coli by Using Human Primary Organoid-Derived Epithelial Monolayers

Over the last decades, Adherent-Invasive Escherichia coli (AIEC) has been linked to the pathogenesis of Crohn’s Disease. AIEC’s characteristics, as well as its interaction with the gut immune system and its role in intestinal epithelial barrier dysfunction, have been extensively studied. Nevertheles...

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Bibliographic Details
Main Authors: Aida Mayorgas, Isabella Dotti, Marta Martínez-Picola, Miriam Esteller, Queralt Bonet-Rossinyol, Elena Ricart, Azucena Salas, Margarita Martínez-Medina
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
organoid-derived epithelial monolayers (ODM)
adherent-invasive E. coli (AIEC)
bacterial infection
intestinal epithelial cells (IECs)
inflammatory bowel disease (IBD)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.646906/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.646906/full

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