Single-molecule characterization of subtype-specific β1 integrin mechanics

Integrins come in subtypes that bind distinct ligands. This work reveals and quantifies subtype-specific mechanical force transmission and assembly of cytoskeleton architectures.

Bibliographic Details
Main Authors: Myung Hyun Jo, Jing Li, Valentin Jaumouillé, Yuxin Hao, Jessica Coppola, Jiabin Yan, Clare M. Waterman, Timothy A. Springer, Taekjip Ha
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35173-w