S1PR1 regulates NDV-induced IL-1β expression via NLRP3/caspase-1 inflammasome

S1PR1 regulates NDV-induced IL-1β expression via NLRP3/caspase-1 inflammasome

Abstract Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the Newcastle disease virus (NDV), an important pathogen harmful to domestic poultry. Virulent NDV strain infection induces IL-1β expression and along with strong inflammatory response, ultimately results i...

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Bibliographic Details
Main Authors: Pei Gao, Shiyuan Zhang, Xinxin Zhang, Chenggang Xu, Libin Chen, Lei Fan, Jinlian Ren, Qiuyan Lin, Bin Xiang, Tao Ren
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Veterinary Research
Subjects:
Newcastle disease virus
IL-1β
S1PR1
MAPK
NLRP3 inflammasome
Online Access:https://doi.org/10.1186/s13567-022-01078-1

Internet

https://doi.org/10.1186/s13567-022-01078-1

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